شنبه ٠١ مهر ١٣٩٦ - 
1 2 3 4 5
 
منو اصلی
صفحه اصلي >  اعضای هیئت علمی >  دکتر شعبانی 
 
 

 

                                 

  

B.S., M.Sc., Ph.D.
Mahdi Shabani
Department of Immunology,
School of Medicine,
Shahid Beheshti University of Medical Sciences, Tehran, Iran;
Tel: +98(21)22439970;
Emails: msshabani@sbmu.ac.ir
    msshabani@yahoo.com
  
PERSONAL FEATURES
Date of Birth:                       23rd August 1978
Gender/ Marital Status:         Male/ Married
Citizenship:                             Iran
 

QUALIFICATIONS:

- B.S.(1997-2001), Medical Laboratory Sciences, Faculty of Para Medicine, Tehran University of Medical Sciences, Tehran, Iran

- M.Sc.(2002-2005), Medical Immunology, Department of Immunology, School of Public Health; Tehran University of Medical Sciences, Tehran, Iran

- Ph.D.(2005-2012), Medical Immunology, Department of Immunology, School of Medicine; Shiraz University of MedicalSciences, Shiraz, Iran

- Sabbatical study (June-November 2011), Lymphocyte signaling, Department of Evolutionary Biology, University of Siena, Siena, Italy

 

POSTS HELD:

2016- till now- Assistant Professor in Immunology, Department of Immunology,

                    School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran 

 

2012- 2016- Assistant Professor in Immunology, Antigen-Antibody Engineering Dept., Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran 

 

2013- 2015- Director of Antigen-Antibody Engineering, Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran

 

2013-2015- Member of Strategic Council of Iranian Medical Biotechnology Network, Ministry of Health and Medical Education

 

2013-2016- Member of Iranian Cancer Network, Ministry of Health and Medical Education

 

 

 

HONOR

1-       Ranking the second in Ph.D. entrance exam (Ministry of Health) of Medical Immunology in 2005.

2-       Ranking the first in M.Sc. entrance exam (Ministry of Health) of Medical Immunology in 2002.

3-       Ranking the second in M.Sc. entrance exam (Tarbiat Modarres University) of Medical Immunology in 2002.

4-       Ranking the second in B.S. entrance exam (Tehran University of Medical Sciences) of Medical Laboratory Sciences in 1999.

5-       Recognized and encouraged as the top student of Shiraz University of Medical Sciences in Ph.D. course (average: 19.49 from 20).

6-       Recognized and encouraged as the top student of Tehran University of Medical Sciences in M.Sc. course (average: 19.38 from 20).

7-       Recognized and encouraged as the top student of Tehran University of Medical Sciences in B.S. course (average: 18.51 from 20).

8-       Recognized and encouraged as the top student of Tehran University of Medical Sciences in Medical technology course (average: 17.65 from 20).

9-       Recognized and encouraged as the chosen researcher and student of Tehran University of Medical Sciences-Avicenna (2007).

10-   ECI Travel Scholarship Award for the European Congress of Immunology (2nd European Congress of Immunology, ECI 2009).

11-   Short-Term (3-month) Fellowship grant fromEuropean Federation of Immunological Societies and Immunology Letters (EFIS) (2011).

12-   Recognized and encouraged as the chosen researcher of Avicenna Research Institute (2014).

 

MEMBERSHIP

- Iranian Society of Immunology and Allergy (2003 till now)

- European Association for Cancer Research (2011 till now)

- Iranian Medical Biotechnology Network (2013-2015)

- Iranian Cancer Network (2013-2016)

- Editorial Board Member of Journal of Unexplored Cancer Data (March 2016)

- Reviewer for Tumor biology, Avicenna Journal of Medical Biotechnology and Iranian Journal of Immunology

 

Organization of meetings and courses

- Assistant of Scientific Secretary in Congress of Basic Science and Knowledge-based production (Tehran, 6-8 February 2016)

- Member of Scientific Committee in Congress of Basic Science and Knowledge-based production (Tehran, 6-8 February 2016)

- Member of Scientific Committee and panel member in 13th International Congress of Immunology and Allergy of Iran (Tabriz, 26-29 April 2016)

- Gene Cloning Workshop presented in in 13th International Congress of Immunology and Allergy of Iran (Tabriz, 26-29 April 2016)

 

       

EXPERIENCES

-Teaching the practical and theoretical courses for post-graduate students at Tehran University of Medical Sciences and Trabbiat Modarres University

 

- Teaching Bioinformatics course for PhD and MSc students of Medical Immunology at Tehran University of Medical Science

 

- Teaching Immunogenetic course for MSc students at Royan Institute

 

- Teaching immunohematology for BS students at Medical branch of Azad University

 

-Experiences in different techniques including: cell culture, RT-PCR, flow cytometry, transfection, gene cloning, recombinant protein production and purification, polyclonal antibody, monoclonal antibody, ELISA, apoptosis, XTT, electrophoresis and immunoblating

 

Principal research interests:

- Cancer vaccine, immunotherapy, cancer animal model, cell signaling

 

Attendance in Workshops:

1- The practical roles of R&D in pharmaceutical based GMP aspects, Institute Pasture of Iran, 10-11 March 2014

 

2- Industrial Scale Production of Monoclonal Antibody, Aryogen, 29 April 2014

 

3- From lab to product in recombinant derivatives field, Institute Pasture of Iran, 27 December 2013

 

 

THESIS

 M.S. course

-Assessment of Ror-1 gene expression for detection and screening of the leukemic cells in patients with Acute Lymphoblastic Leukemia (ALL) (2005)

-Thesis for M.S. degree in Medical Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

-Score: 20 out 20

-Supervisor:

 Prof. Shokri F (PhD), Tehran University of Medical Sciences, Tehran-Iran

 Dr. Rabbani H (PhD), Karolinska institute, Stockholm-Sweden

-Advisors: Dr. Jeddi Tehrani M (PhD), Dr. Sharifian RA (MD) & Dr. Vossough P (MD)

 Ph.D. course

-Investigation of biological activity and expression of human Fc receptor homologe (FcRL)

-Thesis for Ph.D. degree in Medical Immunology, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran.

-Score: 20 out 20

-Supervisor:

 Prof. Shokri F (PhD), Tehran University of Medical Sciences, Tehran-Iran

 Prof. Amirghofran Z (PhD), Shiraz University of Medical Sciences, Fars, Iran

-Advisors: Dr. Rabbani H (PhD), Dr. Jeddi Tehrani M (PhD)

PUBLICATIONS

 

H-index: 8

 

Articles:

1-      Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vosoogh, Ramazan Ali Sharifian, Soheila Gharagozlou, Jalal Khoshnoodi, Tahereh Shahrestani, Mahin Kordmahin, Abdolfattah Sarrafnejad, Mahmood  JeddiTehrani, Hodjatallah Rabbani, Fazel Shokri. Over-expression of Wilm’s Tumor Gene 1(WT1) in Iranian Patients with Acute Myeloblastic Leukemia. IranJ Immunol. 2005; 2: 182-90.

 

2-      Maryam Beigom Mobasheri, Mohammad Hossein Modarressi, Mahdi Shabani, Hossein  Asgarian-Omran, Ramezan-Ali Sharifian, Parvaneh Vossough, Fazel Shokri. Expression of the testis-specific gene, TSGA10, in Iranian patients with acute lymphoblastic leukemia (ALL). Leuk Res.2006; 30:  883-9.

 

 

3-      Hossein Asgarian-Omran, Mahdi Shabani,Parvaneh Vossough, Ramazan A. Sharifian, Mohammad Faranoush, Soheila Gharagozlou, Abdolfattah Sarrafnejad, Jalal Khoshnoodi, Azam Roohi,  Mahmood Jeddi-Tehrani, Hodjatollah Rabbani, Fazel Shokri. Immunophenotyping of Iranian Patients with Acute Lymphoblastic Leukemia (ALL) and its Association to Disease Outcome. IranJ Immunol. 2007; 4: 15-25.

 

4-      Mahdi Shabani, Hossein Asgarian-Omran, Mahmood Jeddi-Tehrani, Soheila gharagozlou, Parvaneh Vosoogh, Mohammad Faranoosh, Ramazan-Ali Sharifian, Gholam R. Toughe, Gholam A. Kardar, Mahin Kordmahin, Jalal Khoshnoodi, Azam Roohi, Farzaneh Towfighi, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Over-expression of orphan receptor tyrosine kinase Ror1 as a putative tumor associated antigen in Iranian patients with acute lymphoblastic leukemia (ALL). Tumor Biol. 2007; 28: 318-26.

 

5-      Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vossough, Ramzan A. Sharifian, Mina Tabrizi,, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani, Hodjatollah Rabbani, Fazel Shokri. Cross-sectional Monitoring of Wilms’ Tumor Gene 1 (WT1) Expression in Iranian Patients with Acute Lymphoblastic Leukemia at Diagnosis, Relapse and Remission. Leuk Lymphoma. 2008; 49: 281-90.

 

6-      Mahdi Shabani, Hossein Asgarian-Omran, Parvaneh Vossough, Ramazan A. Sharifian, Mohammad Faranoush, Soheila Gharagozlou, Jalal Khoshnoodi, Azam Roohi,  Mahmood Jeddi-Tehrani, Hakan Mellstedt, Hodjatollah Rabbani, Fazel Shokri. Expression Profile of Orphan Receptor Tyrosine Kinase (Ror1) and Wilm’s Tumor Gene 1 (WT1) in Different Subsets of B-ALL. Leuk Lymphoma 2008;49:1360-7.

 

7-      Tohid Kazemi, Hossein Asgarian-Omran, Mohammad Hojjat Farsangi, Mahdi Shabani, Ali Memarian. Ramzan A. Sharifian, Seyed Mohammad Razavi, Mahmood Jeddi-Tehrani, Hodjatollah Rabbani, Fazel Shokri. FCRL1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia. Int J Cancer 2008 ;123:2113-9.

 

8-      Tohid Kazemi, Hossein Asgarian-Omran, Ali Memarian, Mahdi Shabani, Ramzan A. Sharifian, Parvaneh Vossough, Bita Ansaripour, Mahmood Jeddi-Tehrani, Hodjatollah Rabbani, Fazel Shokri. Low representation of Fc receptor-like 1-5 molecules in leukemic cells from Iranian patients with acute lymphoblastic leukemia. Cancer Immunol Immunother. 2009 ;58(6):989-96.

 

9-      Mahdi  Shabani,  Shayda  Hemmati  ,  Reza  Hadavi  ,  Zahra  Amirghofran  ,  Mahmood  Jeddi-Tehrani  ,  Hodjattallah  Rabbani  ,  Fazel  Shokri. Optimization of Gene Transfection in Murine Myeloma Cell Lines Using Different Transfection Reagents. AJMB. July-September 2010, 2(3): 123-130.

 

10-  Mahdi Shabani, Hossein Asgarian-Omran, Mohammad Hojjat Farsangi, Parvaneh Vossough, Ramazan A. Sharifian, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani,  Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Comparative expression of Orphan Receptor Tyrosine Kinase (ROR1) in lymphoid and myeloid leukemias. AJMB. July-September 2011, 3(3): 119-125.

 

11-  Amirghofran Z, Malek-Hosseini S, Golmoghaddam H, Kalantar F, Shabani M. Inhibition of nitric oxide production and proinflammatory cytokines by several medicinal plants.Iran J Immunol. 2011 Sep;8(3):159-69.

 

12-  Memarian A, Vosough P, Asgarian-Omran H, Tabrizi M, Shabani M, Shokri F. Differential WNT Gene Expression in Various Subtypes of Acute Lymphoblastic Leukemia. Iran J Immunol. 2012 Mar;9(1):61-71.

 

13-  Shirali S, Aghaei M, Shabani M, Fathi M, Sohrabi M, Moeinifard M. Adenosine induces cell cycle arrest and apoptosis via cyclinD1/Cdk4 and Bcl-2/Bax pathways in human ovarian cancer cell line OVCAR-3.Tumour Biol. 2013 Apr;34(2):1085-95. doi: 10.1007/s13277-013-0650-1. Epub 2013 Jan 24. PMID: 23345014

 

14-  Golmoghaddam H, Amirghofran Z, Aflaki E, Kamali-Sarvestani E, Shabani M, Esmaeilbeig M, Rajabi M. Association of FCRL3 Genotypes with Susceptibility of Iranian Patients to Rheumatoid Arthritis. Immunol Invest. 2013;42(4):296-306. doi: 10.3109/08820139.2013.764314. PMID: 23883198.

 

15-   Shabani M, Hemmati A, Khoshnoodi J, Jeddi-Tehrani M, Rabbani M, Amirghofran Z, Shokri F. Cloning, expression and characterization of recombinant human Fc receptor like (FCRL) 1, 2 and 4 molecules. Iranian Journal of Biotechnology. 2013 August; 11(3): 182-92.

 

16-  Shabani M,Bayat AA, Jeddi-Tehrani M, Rabbani H, Hojjat-Farsangi M, Ulivieri C, Amirghofran Z, Baldari CT, Shokri F.‎Ligation of human Fc receptor like-2 (FCRL2) by specific monoclonal antibodies ‎downregulates B cell receptor mediated signaling. Immunology. 2014 Nov;143(3):341-53. doi: 10.1111/imm.12311.

 

17-  Korosh Khanaki, Mohammad Reza Sadeghi, Mohammad Mehdi Akhondi, Masoud Darabi, Amir Mehdizadeh, Mahdi Shabani, Ali Rahimipour, Mohammad Nouri. High ω-3:ω-6 fatty acids ratio increases fatty acid binding protein 4 and extracellular secretory phospholipase A2IIa in human ectopic endometrial cells. Iran Journal of Reproductive Medicine 2014, 12(11); 755-764.

 

18-  Bayat A, Ghods R, Shabani M, Mahmoudi A, Yeganeh, Hassannia H, Sadeghitabar A, Balay-Goli L, Noutash-Haghighat F, Sarrafzadeh A, Jeddi-Tehrani M. Production and characterization of monoclonal antibodies against human prostate specific antigen. Avicenna journal of medical biotechnology 2015 Jan-Mar;7(1):2-7.

 

19-  Davoud Rostamzadeh, Mohammad Hossein Dabbaghmanesh, Mahdi Shabani, Zahra Amirghofran. Expression Profile of Human Fc Receptor Like 1, 2 and 4 Molecules in Peripheral Blood Mononuclear Cells of Patients with Hashimoto's Thyroiditis and Graves' Disease.  Horm. Metab. Res. 2015 Mar 4. [Epub ahead of print] DOI: 10.1055/s-0035-1545280

 

20-  Mahdi Shabani, Jila Naseri & Fazel Shokri. Receptor tyrosine kinase-like orphan receptor ROR1: A novel target for cancer immunotherapy. Expert Opin Ther Targets 2015 Jul;19(7):941-55. [Epub ahead of print] PMID: 25835638   

 

21-  Jafar Amani, Amir Ghasemi, Reza Ranjbar, Mahdi Shabani, Mahdi Zandemami, Reza Golmohammadi. Immune reactivity of sera obtained from brucellosis patients and vaccinated-rabbits to a fusion protein from Brucella melitensis. Iran J Basic Med Sci. 2015 Apr;18(4):350-5.

 

22-  Sima Hajiahmadi, Mojtaba Panjehpour, Mahmoud Aghaei, Mahdi Shabani. Activation of A2b Adenosine Receptor Regulates Ovarian Cancer Cell Growth: Involvement of
Bax/Bcl-2 and Caspase-3. Biochem Cell Biol. 2015 Mar 16:1-9. PMID: 25877700.

 

23-  Fateme Sadri-Ardalani, Mahdi Shabani, Mohammad Mehdi Amiri, Shaghayegh Emami, Ali Reza Sarrafzadeh, Farzaneh Noutash-Haghighat, Mahmood Jeddi-Tehrani and Fazel Shokri. Antibody response to HER2 extracellular domain and subdomains in mouse following DNA immunization. Tumour Biol. 2016 Jan;37(1):1217-27.

 

 

24-  Mahdi Shabaniand Mohammad Hojjat-Farsang. Targeting Receptor Tyrosine Kinases using Monoclonal Antibodies: the Most Specific Tools for Cancer Targeted Therapy. Curr Drug Targets. 2016;17(14):1687-1703.

 

25-  Narges Zargar Balajam, Mahdi Shabani, Mahmoud Aghaei, Mansoreh Haghighi, Farzad Kompani. Study of T-cell Immunoglobulin-Mucin-3 (TIM-3) expression profile in peripheral blood and bone marrow of Acute Lymphoblastic Leukemia patients. Submitted to Leukemia and Lymphoma. Submitted

 

26-  Fateme Sadri-Ardalani, Moslem Ahmadi, Azam Hemmati, Shaghayegh Emami, Samira Farid, Mohammad Mehdi Amiri, Mahmood Jeddi-Tehrani, Mahdi Shabani and Fazel Shokri. Immunogenicity of Recombinant Extracellular Subdomains of HER2 Molecule in Mice. Submitted

 

27-  Narges Zargar Balajam, Mahdi Shabani, Mansoreh Haghighi, Ahmad Ali Bayat, Mahmoud Aghaei, Study of T-cell Immunoglobulin-Mucin-3 (TIM-3) expression profile in peripheral blood and bone marrow of Acute Lymphoblastic Leukemia patients. Submitted

 

28-  Leili Aghebati Maleki, Mahdi Shabani, Morteza Motallebnezhad, Hamid Nickho, Jafar Majidi, Vahid Younesi, Behzad Baradaran, Jalal Abdolalizadeh, Mehdi Yousefi. Receptor Tyrosine kinase-like Orphan Receptor 1 (ROR-1): Is an Emerging Target for Diagnosis and Therapy of Chronic Lymphocytic Leukemia. Submitted

 

29-  Hajar shali, Mahdi Shabani, Farhad Jadidi-Niaragh, Behzad Baradaran, Fatemeh Atyabi, and Mehdi Yousefi. Co-Delivery of Insulin-like Growth Factor 1 Receptor specific siRNA and Doxorubicin using Chitosan-based Nanoparticles Enhanced Anticancer Efficacy in A549 Lung Cancer Cell Line. Submitted

 

 

 

 

 

Books:

1- Chapter: Monoclonal antibodies for cancer immunotherapy, by: Amir-Hassan Zarnani, Mahmood Bozorgmehr, Mahdi Shabani, Leila Barzegar-Yarmohammadi, Fatemeh Ghaemimanesh, Mahmood Jeddi-Tehrani,  IN: Cancer Immunology - Translational Medicine From Bench to Bedside, Springer-Verlag GmbH, Heidelberg 2015

 

 

 

PRESENTATIONS

 

1-      Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vosoogh, Ramazan AliSharifian, Soheila Gharagozlou, Jalal Khoshnoodi, Tahereh Shahrestani, Mahin Kordmahin, Abdolfattah Sarrafnejad, Mahmood  JeddiTehrani, Hodjatallah Rabbani, Fazel Shokri. Over-expression of Wilm’s Tumor Gene 1(WT1) in Iranian Patients with Acute Myeloblastic Leukemia. 8th Iranian Congress of Immunology and Allergy. May 16-18, 2006 - Tehran, Iran.

 

2-      Mahdi Shabani, Hossein Asgarian-Omran, Mahmood Jeddi-Tehrani, Soheila gharagozlou, Parvaneh Vosoogh, Mohammad Faranoosh, Ramazan-Ali Sharifian, Gholam R. Toughe, Gholam A. Kardar, Mahin Kordmahin, Jalal Khoshnoodi, Azam Roohi, Farzaneh Towfighi, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Over-expression of orphan receptor tyrosine kinase Ror1 as a putative tumor associated antigen in Iranian patients with acute lymphoblastic leukemia (ALL). 8th Iranian Congress of Immunology and Allergy. May 16-18, 2006 - Tehran, Iran.

 

3-      Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vosoogh, Ramazan A. Sharifian, Mohammad Faranoosh,  Soheila Gharagozlou, Jalal Khoshnoodi, Farzaneh Towfighi, Azam Roohi, Mahmood Jeddi-Tehrani, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Expression Profile of Orphan Receptor Tyrosine Kinase (Ror1) and Wilm’s Tumor Gene 1 (WT1) in Different Subsets of B-ALL. 16th European Congress of Immunology – ECI. September 6-9, 2006 - Paris, France.

 

4-      Mahdi Shabani, Hossein Asgarian-Omran, Mahmood Jeddi-Tehrani, Soheila gharagozlou, Parvaneh Vosoogh, Mohammad Faranoosh, Ramazan-Ali Sharifian, Gholam R. Toughe, Gholam A. Kardar, Mahin Kordmahin, Jalal Khoshnoodi, Azam Roohi, Farzaneh Towfighi, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Over-expression of orphan receptor tyrosine kinase Ror1 as a putative tumor associated antigen in Iranian patients with acute lymphoblastic leukemia (ALL).16th European Congress of Immunology – ECI. September  6-9, 2006 - Paris, France.

 

5-      Mohammad Hossein Modarressi, Maryam Beygom Mobasheri, Mahdi Shabani, Hossein Asgarian-Omran, Fazel Shokri. Expression of a new cancer/testis gene, TSGA10, in patients with acute lymphoblastic leukemia (ALL). European Human Genetics Conference. May 6-9, 2006 – Amsterdam, Netherlands.

 

6-       Hossein Asgarian-Omran, Mahdi Shabani, Tahereh Shahrestani, Abdolfattah Sarafnejad, Jalal Khoshnoodi, Parvaneh Vossough, Mohammad Faranoush, Ramzan A. Sharifian, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Fazel Shokri. Immunophenotypic Subtyping of Leukemic Cells from Iranian Patients with Acute Lymphoblastic Leukemia: Association to Disease Outcome. 13th International Congress of Immunology, August 21-25, 2007, Rio de Janeiro, Brazil.

 

7-      Mahdi Shabani,Hossein Asgarian-Omran, Jalal Khoshnoodi, Parvaneh Vossough, Mohammad Faranoush, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Fazel Shokri. Investigation of WT1 gene expression as a reliable tool for monitoring minimal residual disease in acute lymphoblastic leukemia. 13th International Congress of Immunology, August 21-25, 2007, Rio de Janeiro, Brazil.

 

 

8-      Mahdi Shabani, Hossein Asgarian-Omran, Mohammad Hojjat-Farsangi, Parvaneh Vossough, Ramazan A. Sharifian, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Comparative expression of Orphan Receptor Tyrosine Kinase (ROR1) in lymphoid and myeloid leukemias.9th Iranian Congress of Immunology and Allergy. June 17-19, 2008 - Tehran, Iran.

 

9-      Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vossough, Ramazan A. Sharifian, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Monitoring of Minimal Residual Disease in Patients with Acute Lymphoblastic Leukemia using Orphan Receptor Tyrosine Kinase (ROR1) Gene. 9th Iranian Congress of Immunology and Allergy. June 17-19, 2008 - Tehran, Iran.

 

10-  Tohid Kazemi, Hossein Asgarian-Omran, Ali Memarian, Mahdi Shabani, Ramzan A. Sharifian, Parvaneh Vossough, Bita Ansaripour, Mahmood Jeddi-Tehrani, Hodjatollah Rabbani, Fazel Shokri. Low representation of Fc receptor-like 1-5 molecules in leukemic cells from Iranian patients with acute lymphoblastic leukemia.9th Iranian Congress of Immunology and Allergy. June 17-19, 2008 - Tehran, Iran.

 

 

11-  Hossein Gholmoghadam, Saeed Malekhosseini, Mahdi Shabani, Zahra Amirghofran.Study of the effects of native plants on the production of nitric oxide. 9th Iranian Congress of Immunology and Allergy. June 17-19, 2008 - Tehran, Iran.

 

 

12-  Mahdi Shabani, Hossein Asgarian-Omran, Mohammad Hojjat Farsangi, Parvaneh Vossough, Ramazan A. Sharifian, Jalal Khoshnoodi, , Mahmood Jeddi-Tehrani,  Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri.Comparative expression of Orphan Receptor Tyrosine Kinase (ROR1) in lymphoid and myeloid leukemias. 2nd European Congress of Immunology (ECI). Septamber 13-16, 2009-Berlin, Germany.

 

13-  Ali Memarian, HosseinAsgarian-Omran,Mahdi Shabani,Parvaneh Vossough, Jalal Khoshnoodi, , Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Fazel Shokri. Differential expression of WNT genes in leukemic cells from various subtypes of Acute Lymphocytic Leukemia. 2nd European Congress of Immunology (ECI). Septamber 13-16, 2009-Berlin, Germany.

 

14-  Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vossough, Ramazan A. Sharifian, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Fazel Shokri. Monitoring of Minimal Residual Disease in Patients with Acute Lymphoblastic Leukemia using Wilms’ Tumor Gene 1 (WT1) Expression. 10th Iranian Congress of Immunology and Allergy. May 18-20, 2010 - Tehran, Iran.

 

15-  Tohid Kazemi, Hossein Asgarian-Omran, Mahdi Shabani, Jalal Khoshnoodi, Azam Roohi, Hodjatallah  Rabbani,  Fazel Shokri. Fc Receptor-like (FCRL) 1-5 Gene Expression Profiling in Burkitt`s Lymphoma Cell Lines. 10th Iranian Congress of Immunology and Allergy. May 18-20, 2010 - Tehran, Iran.

 

16-  Mahdi Shabani,Azam Hemmati, Ali Ahmad Bayat, Zahra Amirghofran, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Fazel Shokri.  Production and characterization of monoclonal antibodies to human FCRL1 molecules. 10th Iranian Congress of Immunology and Allergy. May 18-20, 2010 - Tehran, Iran.

 

17-  Mahdi Shabani,Sheyda Hemmati, Zahra Amirghofran, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Fazel Shokri. Optimization of Gene Transfection in Murine Myeloma Cell Lines Using Different Transfection Reagents.10th Iranian Congress of Immunology and Allergy. May 18-20, 2010 - Tehran, Iran.

 

18-  Hossein Gholmoghaddam, Zahra Amirghofran, Mahdi Shabani, Eskandar Kamali Sarvestani. FCRL3 polymorphism in Iranian patients with rheumatoid arthritis. 10th Iranian Congress of Immunology and Allergy. May 18-20, 2010 - Tehran, Iran.

 

19-  Hossein Asgarian-Omran, Mahdi Shabani, Parvaneh Vossough, Ramazan A. Sharifian, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani, Hakan Mellstedt, Hodjatallah Rabbani, Fazel Shokri. Monitoring of Minimal Residual Disease in Patients with Acute Lymphoblastic Leukemia using Orphan Receptor Tyrosine Kinase (ROR1) Gene. 14th International Congress of Immunology, August 22-27, 2010, Kobe, Japan.

 

20-  Tohid Kazemi, Hossein Asgarian-Omran, Mahdi Shabani, Jalal Khoshnoodi, Azam Roohi, Hodjatallah  Rabbani,  Fazel Shokri. Fc Receptor-like (FCRL) 1-5 Gene Expression Profiling in Burkitt`s Lymphoma Cell Lines. 14th International Congress of Immunology, August 22-27, 2010, Kobe, Japan.

 

21-  Mahdi Shabani,Azam Hemmati, Jalal Khoshnoodi, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Zahra Amirghofran, Fazel Shokri. Cloning, Expression and Characterization of Recombinant Human Fc Receptor ‎Like (FCRL) 1, 2 and 4 Molecules. 11th Iranian Congress of Immunology and Allergy. April 26-29, 2012 - Tehran, Iran.

 

22-  Mahdi Shabani, Ali Ahmad Bayat, Mahmood Jeddi-Tehrani, Hodjatallah Rabbani, Cristina Ulivieri, Zahra Amirghofran, Cosima Tatiana Baldari and Fazel Shokri. Ligation of human Fc receptor like-2 (FCRL2) by specific monoclonal antibodies downregulates B cell receptor mediated signaling. 15th International Congress of Immunology, August 22-27, 2013, Milan, Italy.

 

23-  Fathollah Kalantar, Saeid M. Hosseini, Hoeesin Gholmoghadam, Mahdi Shabani and Zahra Amirghofran. Inhibition of nitric oxide production and proinflammatory cytokines by several medicinal plants. 15th International Congress of Immunology, August 22-27, 2013, Milan, Italy.

 

24-  Hoeesin Golmoghaddam, Zahra Amirghofran, Elham Aflaki, Eskandar Kamali-Sarvestani, Mahdi Shabani, Zahra Esmaeilbeig, Maryam Rajabi; Association of FCRL3 genotypes with susceptibility of Iranian patients to rheumatoid arthritis. 15th International Congress of Immunology, August 22-27, 2013, Milan, Italy.

 

25-  Mahdi Shabani, Azam Hemmati, Jafar Mahmoudian, Ali Ahmad Bayat, Mahmood Jeddi-Tehrani, Hojatollah Rabbani, Cristina Ulivieri, Zahra Amirghofran, Cosima Tatiana Baldari, Fazel Shokri. Ligation of human Fc receptor like 4 (FCRL4) by specific monoclonal antibodies downregulates B cell receptor mediated signaling. 12th Iranian Congress of Immunology and Allergy. 29th April-2nd May, 2014- Tehran, Iran.

 

26-  Fatemeh Sadri-Ardalani, Mohammad Mehdi Amiri, Shaghayegh Emami, Reza Hadavi, Parisa Yousefi, Fatemeh Ghaemimanesh, Mahmood Jeddi-Tehrani, Mahdi Shabani and Fazel Shokri. Induction of HER2 specific anti tumor antibody response by DNA immunization. 12th Iranian Congress of Immunology and Allergy. 29th April-2nd May, 2014- Tehran, Iran.

 

27-  Shaghayegh Emami, Mahdi Shabani, Samira Shakeri, Reza Hadavi, Farhad Khosravi, Hadi Hassannia, Ahmad Reza Mahmoudi, Layla Balaie-goli, Ali Ahmad Bayat, Mohammad Esmaeil Akbari, Mahmood Jeddi-Tehrani, Fazel Shokri and Hojatollah Rabbani. A new murine monoclonal antibody for screening of human epidermal growth factor receptor-2 (HER2) in breast cancer patients. 12th Iranian Congress of Immunology and Allergy. 29th April-2nd May, 2014- Tehran, Iran.

 

28-  Korosh Khanaki, Mohammad Reza Sadeghi, Mahdi Abedinzadeh, Mohammad Mehdi Akhondi, Mahdi Shabani. Effect of long-chain fatty acids on secretory phospholipase A2IIa of ectopic and matched eutopic endometrial cells in the culture media. 12th Iranian Congress of Immunology and Allergy. 29th April-2nd May, 2014- Tehran, Iran.

 

29-  Davoud Rostamzadeh, Mohammad Hossein Dabbaghmanesh, Mahdi Shabani, Korosh Kalantar, Zahra Amirghofran, Ahmad Hosseini. Study of the expression of FCRL molecules in peripheral blood lymphocytes of patients with Hashimoto’s thyroiditis and Grave’s disease. 12th Iranian Congress of Immunology and Allergy. 29th April-2nd May, 2014- Tehran, Iran.

 

30-  Moslem Ahmadi, Mohammad Mahdi Amiri, Shaghayegh Emami, Reza Hadavi, Parisa Yousefi, Fatemeh Sadri, Mahnaz Bahadori, Samira Farid, Mahmood Jeddi Tehrani, Mahdi Shabani, Fazel Shokri. Immunoprotectivity of HER2 extracellular protein vaccine in HER2-positive breast cancer mouse model. 1st international and 8th annual Tehran Breast Cancer Congress. 28-30th October, 2015, Tehran-Iran.

 

31-   Azam Hemmati, Hadi Hassannia, Sepide Babaei, Shabnam Khademi, Omid Zahed, Farzaneh Haghighat, Parisa Yousefi, Mahdi Shabani, Fatemeh Ghaemimanesh. Detecting Receptor Tyrosine Kinase ROR1 Using a Novel anti-ROR1 Polyclonal Antibody. 8th International Iranian Congress of Laboratory and Clinic. 6-8th  Febrary, 2016- Tehran, Iran.

 

32-  Ahmadi M, Sadri Ardalani F, Hadavi R, Emami Sh, Notash Haghighat F, Zahed O, Bahadori M, Amiri MM, Jeddi-Tehrani M, Shokri F, Shabani M. Vaccination with Recombinant HER2 Extracellular Subdomains Proteins Induces Th1 Response and inhibits Tumor Growth in HER2 Positive Breast Cancer Mouse Model. 13th International Congress of Immunology and Allergy of Iran. 26-29 April 2016, Tabriz-Iran.

 

33-  Sadri-Ardalani F, Ahmadi M, Amiri MM, Hemmati A, Bahadori M, Yousefi P, Jeddi-Tehrani M, Shokri F and Shabani M. Production and assessment of immunogenicity of recombinant HER2 extracellular subdomains: potential tools for tumor vaccination. 13th International Congress of Immunology and Allergy of Iran. 26-29 April 2016, Tabriz-Iran.

 

34-  Farahi F, Shabani M, Zahed O, Hemati A, Hadavi R, Mahmoudi A, Mahmoudian J, Jeddi-Tehrani M, Shokri F. Production and Characterization of Specific Antibody to Recombinant Fibromodulin Protein: A Potential Tool for Chronic Lymphocytic Leukemia Diagnosis. 13th International Congress of Immunology and Allergy of Iran. 26-29 April 2016, Tabriz-Iran

 

35-  Amiri MM, Golara M , Hoseini R, Bahadori M, Khosravi-Eghbal R, Farid S, Kazemi T, Shabani M, Jeddi-Tehrani M, Shokri F. Localization of the extracellular subdomains of human HER2 recognized by HER2 specific monoclonal antibodies. 13th International Congress of Immunology and Allergy of Iran. 26-29 April 2016, Tabriz-Iran

 

 

PROJECTS

 

1. 2003-2005 completed, Collaborator: Assessment of Ror-1 gene expression for detection and screening of the leukemic cells in patients with Acute Lymphoblastic Leukemia (ALL)

 

2. 2003-2005 completed, Collaborator: Analysis of Ror1 gene expression as a marker for detection and monitoring of minimal residual disease in Iranian patients with acute lymphoblastic leukemia (ALL)

 

3. 2007-2012 completed, Collaborator:Investigation of the structural and biological function of human Fc receptor homologe 1, 2 and 4 (FcRL)

 

4. 2007-2012 Collaborator:Targeted immunotherapy by immunotoxin and monoclonal antibody against human Fc receptor homologe 1, 2 and 4 (FcRL) in B-cell malignancies

 

5. 2006-2007 completed, Collaborator:Study of the effects of native plants on the production of nitric oxide

 

6. 2007-2008 completed, Collaborator:Study of human Fc receptor homologe 3 (FCRL3) single nucleotide polymorphism in Iranian patients with Rheumatoid Arthritis

 

7. 2012-2014 completed, Supervisor: Study of the expression of FCRL1, 2, 4 molecules in peripheral blood lymphocytes of patients with Hashimoto’s thyroiditis and Grave`s disease

 

8. 2013-2015 completed, Supervisor: Investigation of anti-tumor protective responses induced by HER2 extracellular domains in a breast cancer mouse model

 

9- 2013-2015 completed, Advisor: Evaluation of TIM3 (T-cell immunoglobin mucin-3) gene expression in the lymphocyte peripheral blood and bone marrow samples from patients with acute lymphoblastic leukemia using Real-Time PCR

 

9. 2013-in progress, Advisor: Anti-FMOD antibody production to evaluate the function of FMOD protein in patients with chronic lymphocytic leukemia

 

10. 2014-in progress, Supervisor: Assessment of cellular immune response and protectivity of HER2 extarcellular subdomains in murine breast cancer model

 

11. 2015-in progress, Advisor: Investigation of the effect of a histone deacetylase Inhibitor - thalidomide - on the gene expression of Fas in human colon cancer Caco-2 and HT-29 cell lines

 

12. 2015-in progress, Advisor: Investigation of anti-tumor properties of the shoot of Euphorbia tehranica ethanolic extract via considering its effect on the genes expression of Bax and Bcl-2 in human colon cancer Caco2 and HT-29 cell lines

 

13.2015-in progress, Advisor: Investigation of the effect of sodium butyrate as a Histone deacetylase inhibitor (HDACi) drug on the gene expression of Fas in human colon cancer Caco2 and HT-29 cell lines

 

 

 

 
پیوندهای مهم
پایگاه اطلاع رسانی مقام معظم رهبری

پایگاه اطلاع رسانی ریاست جمهوری

پایگاه اطلاع رسانی دولت

نهاد نمایندگی مقام معظم رهبری
 
دانشگاه علوم پزشکی و خدمات بهداشتی، درمانی
شهید بهشــتی
آدرس : تهران - بزرگراه شهید چمران خیابان یــمن - خیابان شهید اعــرابی جنب بیمارستان آیت الله طالقانی

تلفن : 23871 - 021
پست الکترونیک : info@sbmu.ac.ir
© تمامی حقوق این سایت متعلق به دانشگاه علوم پزشکی و خدمات بهداشتی، درمانی شهید بهشتی می باشد.